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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCZ1
All Species:
32.42
Human Site:
S599
Identified Species:
64.85
UniProt:
Q86YW0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YW0
NP_149114.2
608
70411
S599
G
E
S
L
E
P
A
S
L
F
V
Y
V
W
Y
Chimpanzee
Pan troglodytes
XP_001160159
608
70343
S599
G
E
S
L
E
P
A
S
L
F
V
Y
V
W
Y
Rhesus Macaque
Macaca mulatta
XP_001096056
641
74533
S632
G
E
S
L
E
P
A
S
L
F
V
Y
V
W
Y
Dog
Lupus familis
XP_543784
711
81950
A702
G
E
S
L
E
P
A
A
L
F
I
Y
V
W
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4D7
647
74595
S637
G
A
N
L
E
P
S
S
L
F
I
Y
V
W
Y
Rat
Rattus norvegicus
Q5FX52
645
74297
S635
G
A
N
L
E
P
S
S
L
F
I
Y
V
W
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
T728
G
D
Q
Y
P
S
A
T
L
F
V
K
I
Q
I
Chicken
Gallus gallus
Q2VRL0
637
72514
S629
G
G
K
L
E
P
A
S
L
F
V
Y
V
W
Y
Frog
Xenopus laevis
Q32NH8
758
87399
S741
G
T
K
I
P
P
A
S
L
F
V
H
I
R
V
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
T760
G
S
T
L
S
P
A
T
L
F
I
H
V
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39033
581
66104
K573
G
E
K
Y
K
S
V
K
L
L
V
K
V
E
F
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
T861
G
E
Q
Y
I
F
C
T
L
F
I
H
T
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
90.3
69.9
N.A.
71.4
70.8
N.A.
34.6
59.9
39.1
34
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
92.3
77.5
N.A.
81.9
81.7
N.A.
52.8
72.2
53.4
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
33.3
86.6
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
53.3
86.6
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
67
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
50
0
0
59
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
92
0
0
0
0
9
% F
% Gly:
100
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
42
0
17
0
17
% I
% Lys:
0
0
25
0
9
0
0
9
0
0
0
17
0
9
0
% K
% Leu:
0
0
0
67
0
0
0
0
100
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
17
75
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
0
0
0
0
0
0
0
0
17
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
9
34
0
9
17
17
59
0
0
0
0
0
0
0
% S
% Thr:
0
9
9
0
0
0
0
25
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
59
0
75
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
0
% W
% Tyr:
0
0
0
25
0
0
0
0
0
0
0
59
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _